Prof Pablo Cruces Ilich Médico Cirujano(Concep), Especialista en Pediatría (PUC)
Area Investigación
Medicina Experimental
BIOGRAFIA
Médico Cirujano (Universidad de Concepción), Especialista en Pediatría (Pontificia Universidad Católica de Chile), Sub-especialista en Medicina Intensiva Pediátrica (Facultad de Medicina Clínica Alemana Universidad del Desarrollo).
Se desempeña desde el 2013 como investigador del Centro de Investigación en Medicina Veterinaria, además de participar en docencia de pregrado (Fisiología, Fisiopatología e Internado de Animales menores) y postgrado (Avances en Medicina Intensiva y tutor de tesis doctorales).
Desarrollo paralelo de proyectos de investigación clínica y experimental, especialmente en áreas de Ventilación Mecánica, Síndrome de Distrés Respiratorio Agudo, Daño Pulmonar Inducido por Ventilación Mecánica, Mecanotransducción, Monitorización Hemodinámica Avanzada y Síndrome Compartimental.
Participación en 12 proyectos de investigación, 6 de ellos como Investigador responsable (incluyendo Fondecyt 11075041) y en los restantes como coinvestigador (incluyendo Fondecyt 1130428)
Editor de Sección “Artículos Originales” de la Revista Chilena de Pediatría, de reciente indización en PubMed. Autor de más de 60 publicaciones nacionales e internacionales.
VER PUBLICACIONES CIENTIFICAS Y PERFIL EN: Portal de Investigadores Universidad Andrés Bello
PUBLICACIONES
Cruces, P., Retamal, J., Damián, A., Lago, G., Blasina, F., Oviedo, V., Medina, T., Pérez, A., Vaamonde, L., Dapueto, R., González-Dambrauskas, S., Serra, A., Monteverde-Fernandez, N., Namías, M., Martínez, J. & Hurtado, D. E., dic. 2024, A machine-learning regional clustering approach to understand ventilator-induced lung injury: a proof-of-concept experimental study En: Intensive Care Medicine Experimental. 12, 1, 60.
Paris, E., Daza, P., Tapia, L., Díaz, J. P., Romero, P. C., Castillo, A., González, C., Endeiza, M. L., Jofré, L., Castro, F., Zamorano, A., Rodríguez, J., Acevedo, J., Cruz, T. S., González, J., Escárate, R., Moreno, J. P. & Cisternas, P., 2024, Estrategias y recomendaciones para enfrentar la enfermedad por virus respiratorio sincicial el año 2024 En: Andes Pediatrica. 95, 1, p. 17-23 7 p.
Juan Sebastián Barajas-Romero 1, Pablo Vásquez-Hoyos 2, Rosalba Pardo 3, Juan Camilo Jaramillo-Bustamante 4, Regina Grigolli 5, Nicolas Monteverde-Fernández 6, Sebastián Gonzalez-Dambrauskas 7, Roberto Jabornisky 8, Pablo Cruces 9, Adriana Wegner 10, Franco Díaz 11, Pietro Pietroboni 12; LARed Network. 2024 Factors associated with prolonged mechanical ventilation in children with pulmonary failure: Cohort study from the LARed Network registry. Medicina Intensiva. 48, 1, p. 23-36 14 p.
Villa, B., Erranz, B., Cruces, P., Retamal, J. & Hurtado, D. E., jun. 2024, Mechanical and morphological characterization of the emphysematous lung tissue En: Acta Biomaterialia. 181, p. 282-296 15 p.
Cruces, P., Erranz, B., Pérez, A., Reveco, S., González, C., Retamal, J., Poblete, D., Hurtado, D. E. & Díaz, F., 15 abr. 2024, Noninvasive Continuous Positive Airway Pressure Is a Lung- and Diaphragm-protective Approach in Self-inflicted Lung Injury En: American Journal of Respiratory and Critical Care Medicine. 209, 8, p. 1022-1025 4
Cruces, P., Reveco, S., Caviedes, P. & Díaz, F., 1 abr. 2024, Respiratory System Compliance Accurately Assesses the «Baby Lung» in Pediatric Acute Respiratory Distress Syndrome En: American Journal of Respiratory and Critical Care Medicine. 209, 7, p. 890-893 4 p.
Cruces, P., Moreno, D., Reveco, S., Ramírez, Y. & Díaz, F., 2024, Ventilatory load reduction by combined mild hypothermia and ultraprotective mechanical ventilation strategy in severe COVID-19-related acute respiratory distress syndrome: A physiological study En: Turkish Journal of Emergency Medicine. 24, 2, p. 117-121 5 p.
Cruces, P., Moreno, D., Reveco, S., Améstica, M., Araneda, P., Ramirez, Y., Vásquez-Hoyos, P. & Díaz, F., oct. 2023, Capnometry after an inspiratory breath hold, PLATCO2, as a surrogate for in mild to moderate pediatric acute respiratory distress syndrome: A feasibility study En: Pediatric Pulmonology. 58, 10, p. 2899-2905 7 p.
Emeriaud G, López-Fernández YM, Iyer NP, Bembea MM, Agulnik A, Barbaro RP, Baudin F, Bhalla A, Brunow de Carvalho W, Carroll CL, Cheifetz IM, Chisti MJ, Cruces P, Curley MAQ, Dahmer MK, Dalton HJ, Erickson SJ, Essouri S, Fernández A, Flori HR, Grunwell JR, Jouvet P, Killien EY, Kneyber MCJ, Kudchadkar SR, Korang SK, Lee JH, Macrae DJ, Maddux A, Modesto I Alapont V, Morrow BM, Nadkarni VM, Napolitano N, Newth CJL, Pons-Odena M, Quasney MW, Rajapreyar P, Rambaud J, Randolph AG, Rimensberger P, Rowan CM, Sanchez-Pinto LN, Sapru A, Sauthier M, Shein SL, Smith LS, Steffen K, Takeuchi M, Thomas NJ, Tse SM, Valentine S, Ward S, Watson RS, Yehya N, Zimmerman JJ, Khemani RG; Second Pediatric Acute Lung Injury Consensus Conference (PALICC-2) Group on behalf of the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network. Executive Summary of the Second International Guidelines for the Diagnosis and Management of Pediatric Acute Respiratory Distress Syndrome (PALICC-2) PALICC-2, 1 feb. 2023, En: Pediatric Critical Care Medicine. 24, 2, p. 143-168 26 p.
Domínguez-Rojas, J., Munoz, Á. C., Luna-Delgado, Y., Alvarado-Gamarra, G., Flores, G. Q., Caqui-Vilca, P., Atamari-Anahui, N., Ramírez, C. M. M., Tello-Pezo, M., Cruces, P., Vásquez-Hoyos, P. & Díaz, F., 1 may. 2023, Mecánica pulmonar en el síndrome de distrés respiratorio agudo pediátrico asociado a COVID-19 aguda y MIS-C En: Andes Pediatrica. 94, 3, p. 350-360 11 p.
Bhalla, A., Baudin, F., Takeuchi, M. & Cruces, P., 1 feb. 2023, Monitoring in Pediatric Acute Respiratory Distress Syndrome: From the Second Pediatric Acute Lung Injury Consensus Conference En: Pediatric Critical Care Medicine. 24, 12 Suppl 2, p. S112-S123
Cruces, P., Erranz, B., González, C. & Diaz, F., 15 mar. 2023, Morphological Differences between Patient Self-inflicted and Ventilator-induced Lung Injury: An Experimental Study En: American Journal of Respiratory and Critical Care Medicine. 207, 6, p. 780-783 4 p.
Emeriaud, G., Pons-Odena, M., Bhalla, A. K., Shein, S. L., Killien, E. Y., Modesto I Alapont, V., Rowan, C., Baudin, F., Lin, J. C., Gregoire, G., Napolitano, N., Mayordomo-Colunga, J., Diaz, F., Cruces, P., Medina, A., Smith, L. & Khemani, R. G., 1 sep. 2023, En: Pediatric Critical Care Medicine. 24, 9, p. 715-726 12 p.
Guillaume Emeriaud, Marti Pons-Òdena, Anoopindar K Bhalla, Steven L Shein, Elizabeth Y Killien, Vicent Modesto I Alapont, Courtney Rowan, Florent Baudin, John C Lin, Gabrielle Grégoire, Natalie Napolitano, Juan Mayordomo-Colunga Franco Diaz , Pablo Cruces, Alberto Medina, Lincoln Smith, Robinder G Khemani; Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology (PARDIE) Investigators and Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network Noninvasive Ventilation for Pediatric Acute Respiratory Distress Syndrome: Experience from the 2016/2017 Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology Prospective Cohort Study Pediatr Crit Care Med . 2023 Sep 1;24(9):715-726. doi: 10.1097/PCC.0000000000003281.
Cruces, P., 1 feb. 2023Pediatric Acute Respiratory Distress Syndrome: Approaches in Mechanical Ventilation, En: Pediatric Critical Care Medicine. 24, 2, p. E104-E114
Cruces, P., Moreno, D., Reveco, S., Ramirez, Y. & Díaz, F., 1 sep. 2023, Plateau Pressure and Driving Pressure in Volume- and Pressure-Controlled Ventilation: Comparison of Frictional and Viscoelastic Resistive Components in Pediatric Acute Respiratory Distress Syndrome En: Pediatric Critical Care Medicine. 24, 9, p. 750-759 10 p.
Cruces, P., Erranz, B. & Diaz, F., 15 may. 2023, En: American Journal of Respiratory and Critical Care Medicine. 207, 10, p. 1407-1408 2 p.
Kneyber, M. C. J., Khemani, R. G., Bhalla, A., Blokpoel, R. G. T., Cruces, P., Dahmer, M. K., Emeriaud, G., Grunwell, J., Ilia, S., Katira, B. H., Lopez-Fernandez, Y. M., Rajapreyar, P., Sanchez-Pinto, L. N. & Rimensberger, P. C., 1 feb. 2023, Understanding clinical and biological heterogeneity to advance precision medicine in paediatric acute respiratory distress syndrome En: The Lancet. Respiratory medicine. 11, 2, p. 197-212 16 p.
Díaz, F., Kehr, J., Cores, C., Rubilar, P., Medina, T., Vargas, C. & Cruces, P., abr. 2022, Clinical and organizational framework of repurposing pediatric intensive care unit to adult critical care in a resource-limited setting: Lessons from the response of an urban general hospital to the COVID-19 pandemicEn: Journal of Critical Care. 68, p. 59-65 7 p.
Araos, J., Cruces, P., Martin-Flores, M., Donati, P., Gleed, R. D., Boullhesen-Williams, T., Perez, A., Staffieri, F., Retamal, J., Vidal Melo, M. F. & Hurtado, D. E., 14 mar. 2022,Distribution and Magnitude of Regional Volumetric Lung Strain and Its Modification by PEEP in Healthy Anesthetized and Mechanically Ventilated Dogs En: Frontiers in Veterinary Science. 9, 839406.
Jaime Fernández-Sarmiento 1, Daniela Carla De Souza 2, Anacaona Martinez 3, Victor Nieto 4, Jesús López-Herce 5, Vanessa Soares Lanziotti 6, María Del Pilar Arias López 7, Werther Brunow De Carvalho 8, Claudio F Oliveira 9, Juan Camilo Jaramillo-Bustamante 10, Franco Díaz 11, Adriana Yock-Corrales 12, Silvina Ruvinsky 13, Manuel Munaico 14, Viviana Pavlicich 15, Ricardo Iramain 16, Marta Patricia Márquez 17, Gustavo González 18, Mauricio Yunge 19, Cristian Tonial 20, Pablo Cruces 21, Gladys Palacio 22, Carolina Grela 23, Maria Slöcker-Barrio 24, Santiago Campos-Miño 25, Sebastian González-Dambrauskas 26, Nelson L Sánchez-Pinto 27 28, Pedro Celiny García 29, Roberto Jabornisky 30 Latin American Consensus on the Management of Sepsis in Children: Sociedad Latinoamericana de Cuidados Intensivos Pediátricos [Latin American Pediatric Intensive Care Society] (SLACIP) Task Force: Executive Summary J Intensive Care Med . 2022 Jun;37(6):753-763. doi: 10.1177/08850666211054444.
Fernández-Sarmiento, J., De Souza, D. C., Martinez, A., Nieto, V., López-Herce, J., Soares Lanziotti, V., Arias López, M. D. P., De Carvalho, W. B., Oliveira, C. F., Jaramillo-Bustamante, J. C., Díaz, F., Yock-Corrales, A., Ruvinsky, S., Munaico, M., Pavlicich, V., Iramain, R., Márquez, M. P., González, G., Yunge, M. & Tonial, C. y 9 otros, , jun. 2022, En: Journal of Intensive Care Medicine. 37, 6, p. 753-763 11 p.
Anoopindar K Bhalla 1 2, Margaret J Klein 3, Vicent Modesto I Alapont 4, Guillaume Emeriaud 5, Martin C J Kneyber 6 7, Alberto Medina 8, Pablo Cruces 9 10, Franco Diaz 11 12, Muneyuki Takeuchi 13, Aline B Maddux 14 15, Peter M Mourani 16, Cristina Camilo 17, Benjamin R White 18, Nadir Yehya 19, John Pappachan 20 21, Matteo Di Nardo 22, Steven Shein 23, Christopher Newth 3 24, Robinder Khemani 3 24; Mechanical power in pediatric acute respiratory distress syndrome: a PARDIE study Crit Care 2022 Jan 3;26(1):2. doi: 10.1186/s13054-021-03853-6.
Raúl, B. B., Díaz, F., Cores, C., Francisca, C. Z. & Cruces, P., 1 jul. 2022, Mielitis flácida aguda e infeccion por enterovirus: una enfermedad grave emergent Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network, 3 ene. 2022, En: Critical care (London, England). 26, 1, p. 2 1 p., 2. En: Andes Pediatrica. 93, 4, p. 552-560 9 p.
Bachmann, M. C., Cruces, P., Díaz, F., Oviedo, V., Goich, M., Fuenzalida, J., Damiani, L. F., Basoalto, R., Jalil, Y., Carpio, D., Hamidi Vadeghani, N., Cornejo, R., Rovegno, M., Bugedo, G., Bruhn, A. & Retamal, J., 25 jul. 2022, Spontaneous breathing promotes lung injury in an experimental model of alveolar collapse En: Scientific Reports. 12, 1, p. 12648 12648.
Diaz, F., Bustos B, R., Yagnam, F., Karsies, T. J., Vásquez-Hoyos, P., Jaramillo-Bustamante, J. C., Gonzalez-Dambrauskas, S., Drago, M. & Cruces, P., 15 nov. 2021,Comparison of Interleukin-6 Plasma Concentration in Multisystem Inflammatory Syndrome in Children Associated With SARS-CoV-2 and Pediatric Sepsis En: Frontiers in Pediatrics. 9, 756083.
Díaz, F., González-Dambrauskas, S., Cristiani, F., Casanova, D. R. & Cruces, P., 1 oct. 2021 Driving Pressure and Normalized Energy Transmission Calculations in Mechanically Ventilated Children Without Lung Disease and Pediatric Acute Respiratory Distress Syndrome, En: Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 22, 10, p. 870-878 9 p.
Araos, J., Alegria, L., Garcia, A., Cruces, P., Soto, D., Erranz, B., Salomon, T., Medina, T., Garcia, P., Dubó, S., Bachmann, M. C., Basoalto, R., Valenzuela, E. D., Rovegno, M., Vera, M., Retamal, J., Cornejo, R., Bugedo, G. & Bruhn, A., nov. 2021,Effect of positive end-expiratory pressure on lung injury and haemodynamics during experimental acute respiratory distress syndrome treated with extracorporeal membrane oxygenation and near-apnoeic ventilation En: British Journal of Anaesthesia. 127, 5, p. 807-814 8 p.
Ingreso en cuidados intensivos debido a bronquiolitis grave en Colombia: ¿dónde nos encontramos en relación con el resto de Latinoamérica? Red Pediátrica de Latinoamérica (LARed) Network & Colaboradores de la Red Pediátrica de Latinoamérica (LARed) Network, oct. 2021, En: Medicina Intensiva. 45, 7, p. e18-e21
Bustos B, R., Jaramillo-Bustamante, J. C., Vasquez-Hoyos, P., Cruces, P. & Díaz, F., 2021, Pediatric Inflammatory Multisystem Syndrome Associated with SARS-CoV-2: A Case Series Quantitative Systematic Review En: Pediatric Emergency Care. 37, 1, p. 44-47 4 p.
Díaz, F., Cores, C., Atenas, O., Rodríguez, N., Bustos, R. & Cruces, P., 1 jul. 2021 Rationale of Therapeutic Plasma Exchange as Rescue Immunomodulatory Treatment for MIS-C With Multiorgan Failure, En: The Pediatric infectious disease journal. 40, 7, p. e259-e262
Cruces, P., 1 nov. 2021,Sepsis desde la perspectiva de países de medianos y bajos ingresos En: Andes Pediatrica. 92, 6, p. 829-830 2 p.
Bustos B, R., Hickmann O, L., Cruces R, P. & Díaz, F., oct. 2021, Therapeutic plasma exchange in critically ill children: experience of the pediatric intensive care unit of two centers in Chile En: Transfusion and Apheresis Science. 60, 5, 103181.
McArdle AJ, Vito O, Patel H, Seaby EG, Shah P, Wilson C, Broderick C, Nijman R, Tremoulet AH, Munblit D, Ulloa-Gutierrez R, Carter MJ, De T, Hoggart C, Whittaker E, Herberg JA, Kaforou M, Cunnington AJ, Levin M; BATS Consortium.nTreatment of Multisystem Inflammatory Syndrome in Children BATS Consortium, 1 jul. 2021, En: New England Journal of Medicine. 385, 1, p. 11-22 12 p.
Cruces, P., Retamal, J., Hurtado, D. E., Erranz, B., Iturrieta, P., González, C. & Díaz, F., 10 ago. 2020, A physiological approach to understand the role of respiratory effort in the progression of lung injury in SARS-CoV-2 infection En: Critical Care. 24, 1, 494.
Dubo, S., Oviedo, V., Garcia, A., Alegriá, L., Garciá, P., Valenzuela, E. D., Damiani, L. F., Araos, J., Medina, T., Bachmann, M. C., Basoalto, R., Bravo, S., Soto, D., Cruces, P., Guzmán, P., Retamal, J., Cornejo, R., Bugedo, G., Brebi, P. & Bruhn, A., 2020, Low spontaneous breathing effort during extracorporeal membrane oxygenation in a porcine model of severe acute respiratory distress syndrome En: Anesthesiology. p. 1106-1117 12 p.
Cruces, P., Cores, C., Rubilar, P., Medina, T. & Díaz, F., 1 may. 2020, Manejo de adultos críticamente enfermos en una unidad de cuidados intensivos pediátricos como respuesta a pandemia por sars-cov2 En: Revista Chilena de Pediatria. 91, 3, p. 472-474 3 p.
Hurtado, D. E., Erranz, B., Lillo, F., Sarabia-Vallejos, M., Iturrieta, P., Morales, F., Blaha, K., Medina, T., Diaz, F. & Cruces, P., 1 dic. 2020, Progression of regional lung strain and heterogeneity in lung injury: assessing the evolution under spontaneous breathing and mechanical ventilation En: Annals of Intensive Care. 10, 1, 107.
Variabilidad terapéutica en lactantes con bronquiolitis hospitalizados en unidades de cuidados intensivos latinoamericanas LARed Colaborativa Pediátrica de Latinoamérica (LARed Network), 1 mar. 2020, En: Revista Chilena de Pediatria. 91, 2, p. 216-225 10 p.
Díaz, F. & Cruces, P., 1 mar. 2019,¿Debemos utilizar las directrices de la campaña sobreviviendo a la sepsis en niños con sepsis temprana? Enfoque en infusión inicial rápida de fluidos En: Revista Chilena de Pediatria. 90, 2, p. 133-136 4 p.
Díaz, F., González-Dambrauskas, S., Lee, J. H. & Cruces, P., 1 may. 2019,Consideraciones geográficas en la interpretación de los resultados de revisiones sistemáticas y meta-análisis: Fluidos en sepsis pediátrica En: Revista Chilena de Pediatria. 90, 3, p. 247-249 3 p.
Yunge, M., Cordero, J., Martinez, D., Bustos, R., Wegner, A., Castro, M., Arrau, L., Diaz, B., Dalmazzo, R., Hickmann, L., Lapadula, M., Yañez, L., Roque, J., Cecchetti, C., Bravo, P., Cruces, P., Acuña, C., Oyaguez, P., Miras, A. & Morales, A. y 11 otros, , 1 feb. 2019, Effectiveness of two targeted temperature management methods after pediatric postcardiac arrest: A multicenter international study En: Pediatric Critical Care Medicine. 20, 2, p. E77-E82
Risk Factors for Mortality in Pediatric Postsurgical versus Medical Severe Sepsis SPROUT Investigators & Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network, oct. 2019, En: Journal of Surgical Research. 242, p. 100-110 11 p.
Cruces P, Erranz B, Lillo F, Sarabia-Vallejos MA, Iturrieta P, Morales F, Blaha K, Medina T, Diaz F, Hurtado DE. 2019 Mapping regional strain in anesthetised healthy subjects during spontaneous ventilation. BMJ Open Respir Res. 2019 Oct 28;6(1):e000423. doi: 10.1136/bmjresp-2019-000423. eCollection 2019.
Araos J, Alegria L, Garcia P, Cruces P, Soto D, Erranz B, Amthauer M, Salomon T, Medina T, Rodriguez F, Ayala P, Borzone GR, Meneses M, Damiani F, Retamal J, Cornejo R, Bugedo G, Bruhn 2019 A. Near-Apneic Ventilation Decreases Lung Injury and Fibroproliferation in an Acute Respiratory Distress Syndrome Model with Extracorporeal Membrane Oxygenation. Am J Respir Crit Care Med. 2019 Mar 1;199(5):603-612. doi: 10.1164/rccm.201805-0869OC.
Díaz F, Cruces P 2019 Should we resuscitate children with early sepsis according to the Surviving Sepsis Campaign Guidelines? Focus on initial rapid fluid infusion Rev Chil Pediatr. 2019 Apr;90(2):133-136. doi: 10.32641/rchped.v90i2.983. Spanish. No abstract available.
Cruces P, González-Dambrauskas S, Cristiani F, Martínez J, Henderson R, Erranz B, Díaz F. 2018 Positive end-expiratory pressure improves elastic working pressure in anesthetized children. BMC Anesthesiol. 2018 Oct 24;18(1):151. doi: 10.1186/s12871-018-0611-8.
Díaz F, Nuñez MJ, Pino P, Erranz B, Cruces P. 2018 Implementation of preemptive fluid strategy as a bundle to prevent fluid overload in children with acute respiratory distress syndrome and sepsis. BMC Pediatr. 2018 Jun 26;18(1):207. doi: 10.1186/s12887-018-1188-6.
Cruces P, Lillo P, Salas C, Salomon T, Lillo F, González C, Pacheco A, Hurtado DE. 2018 Renal Decapsulation Prevents Intrinsic Renal Compartment Syndrome in Ischemia-Reperfusion-Induced Acute Kidney Injury: A Physiologic Approach. Crit Care Med. 2018 Feb;46(2):216-222. doi: 10.1097/CCM.0000000000002830.
Cruces P, González-Dambrauskas S, Quilodrán J, Valenzuela J, Martínez J, Rivero N, Arias P, Díaz F. 2017 Respiratory mechanics in infants with severe bronchiolitis on controlled mechanical ventilation. BMC Pulm Med. 2017 Oct 6;17(1):129. doi: 10.1186/s12890-017-0475-6.
Araos J, Alegría L, García P, Damiani F, Tapia P, Soto D, Salomon T, Rodriguez F, Amthauer M, Erranz B, Castro G, Carreño P, Medina T, Retamal J, Cruces P, Bugedo G, Bruhn A. 2016 Extracorporeal membrane oxygenation improves survival in a novel 24-hour pig model of severe acute respiratory distress syndrome. Am J Transl Res. 2016 Jun 15;8(6):2826-37. eCollection 2016.
Erranz B, Díaz F, Donoso A, Salomón T, Carvajal C, Torres MF, Cruces P. 2015 Decreased lung compliance increases preload dynamic tests in a pediatric acute lung injury model. Rev Chil Pediatr. 2015 Nov-Dec;86(6):404-9. doi: 10.1016/j.rchipe.2015.06.023. Epub 2015 Oct 21.
Díaz F, Erranz B, Donoso A, Salomon T, Cruces P. 2015 Influence of tidal volume on pulse pressure variation and stroke volume variation during experimental intra-abdominal hypertension. BMC Anesthesiol. 2015 Sep 22;15:127. doi: 10.1186/s12871-015-0105-x.
Cruces P, Salas C, Lillo P, Salomon T, Lillo F, Hurtado DE. 2014 The renal compartment: a hydraulic view. Intensive Care Med Exp. 2014 Dec;2(1):26. doi: 10.1186/s40635-014-0026-x. Epub 2014 Oct 23.
Valenzuela J, Araneda P, Cruces P. 2014 Weaning from mechanical ventilation in paediatrics. State of the art. Arch Bronconeumol. 2014 Mar;50(3):105-12. doi: 10.1016/j.arbres.2013.02.003. Epub 2013 Mar 29. Review. English, Spanish.
Cruces P, Erranz B, Donoso A, Carvajal C, Salomón T, Torres MF, Díaz F 2013 Mild hypothermia increases pulmonary anti-inflammatory response during protective mechanical ventilation in a piglet model of acute lung injury. Paediatr Anaesth. 2013 Nov;23(11):1069-77. doi: 10.1111/pan.12209. Epub 2013 Jun 3.
Díaz F, Erranz B, Donoso A, Carvajal C, Salomón T, Torres M, Cruces P. 2013 Surfactant deactivation in a pediatric model induces hypovolemia and fluid shift to the extravascular lung compartment. Paediatr Anaesth. 2013 Mar;23(3):250-7. doi: 10.1111/pan.12037. Epub 2012 Oct 9.
Cruces P, Donoso A, Valenzuela J, Díaz F. 2013 Respiratory and hemodynamic effects of a stepwise lung recruitment maneuver in pediatric ARDS: a feasibility study. Pediatr Pulmonol. 2013 Nov;48(11):1135-43. doi: 10.1002/ppul.22729. Epub 2012 Dec 19.
Arriagada D, Donoso A, Cruces P, Díaz F. 2012 Congenital syphilis: presenting as septic shock alter the neonatal period Rev Chilena Infectol. 2012 Oct;29(5):558-63. doi: 10.4067/S0716-10182012000600017. Spanish.
Díaz F, Donoso A, Carvajal C, Salomón T, Torres M, Erranz B, Cruces P. 2012 Veno-arterial difference of carbon dioxide as a predictor of low cardiac output in an experimental pediatric model. Rev Med Chil. 2012 Jan;140(1):39-44. doi: /S0034-98872012000100005. Epub 2012 Apr 12. Spanish.
Cruces P, Ronco R, Erranz B, Conget P, Carvajal C, Donoso A, Díaz F. 2011 Mild hypothermia attenuates lung edema and plasma interleukin-1β in a rat mechanical ventilation-induced lung injury model. Exp Lung Res. 2011 Nov;37(9):549-54. doi: 10.3109/01902148.2011.616983.
Donoso A, Cruces P, Camacho J, Ríos JC, Paris E, Mieres JJ. 2007 Acute respiratory distress syndrome resulting from inhalation of powdered copper. Clin Toxicol (Phila). 2007 Sep;45(6):714-6.
Donoso AF, Cruces PI, Saitúa FJ, Herrera P, Camacho JF, León JA. 2006 Intraoperative high frequency oscillatory ventilation in 2 children undergoing lung surgery. Rev Esp Anestesiol Reanim. 2006 Jan;53(1):46-9. Spanish.